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TitleDifferent Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.
Journal, issue, pagesMol. Pharmacol., Vol. 74, Page 1554-, Year 2008
Publish dateJan 17, 2008 (structure data deposition date)
AuthorsFruchart-Gaillard, C. / Mourier, G. / Marquer, C. / Stura, E. / Birdsall, N.J.M. / Servent, D.
External linksMol. Pharmacol. / PubMed:18784346
MethodsX-ray diffraction
Resolution1.39 Å
Structure data

PDB-2vlw:
Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative.
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • dendroaspis angusticeps (eastern green mamba)
KeywordsTOXIN / ACETYLCHOLINE RECEPTOR INHIBITOR / GREEN MAMBA SNAKE TOXIN / HM1 MUSCARINIC RECEPTOR / SECRETED / NEUROTOXIN / DIIODOTYROSINE / MUSCARINIC TOXIN / POSTSYNAPTIC NEUROTOXIN

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