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Structure paper

TitleStructures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 31633-31640, Year 2008
Publish dateAug 27, 2008 (structure data deposition date)
AuthorsMace, P.D. / Linke, K. / Feltham, R. / Schumacher, F.R. / Smith, C.A. / Vaux, D.L. / Silke, J. / Day, C.L.
External linksJ. Biol. Chem. / PubMed:18784070
MethodsX-ray diffraction
Resolution2 - 3.4 Å
Structure data

PDB-3eb5:
Structure of the cIAP2 RING domain
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3eb6:
Structure of the cIAP2 RING domain bound to UbcH5b
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • xenopus laevis (African clawed frog)
KeywordsAPOPTOSIS / RING domain / Metal-binding / Zinc-finger / LIGASE / E2 / Ubl conjugation pathway

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