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| Title | Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding |
|---|---|
| Journal, issue, pages | Biochemistry, Vol. 47, Page 10677-10684, Year 2008 |
| Publish date | Dec 6, 2007 (structure data deposition date) |
Authors | Thackray, S.J. / Bruckmann, C. / Anderson, J.L.R. / Campbell, L.P. / Xiao, R. / Zhao, L. / Mowat, C.G. / Forouhar, F. / Tong, L. / Chapman, S.K. |
External links | Biochemistry / PubMed:18783250 |
| Methods | X-ray diffraction |
| Resolution | 1.9 - 2.15 Å |
| Structure data | ![]() PDB-3bk9: ![]() PDB-3e08: |
| Chemicals | ![]() ChemComp-TRP: ![]() ChemComp-HEM: ![]() ChemComp-HOH: |
| Source |
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Keywords | OXIDOREDUCTASE / tryptophan dioxygenase / H55A mutant / heme / TDO / tryptophan 2 / 3-dioxygenase / H55S / Dioxygenase |
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xanthomonas campestris pv. campestris (bacteria)
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