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Structure paper

TitleComputational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
Journal, issue, pagesJ. Mol. Biol., Vol. 382, Page 1265-1275, Year 2008
Publish dateJan 30, 2008 (structure data deposition date)
AuthorsReynolds, K.A. / Hanes, M.S. / Thomson, J.M. / Antczak, A.J. / Berger, J.M. / Bonomo, R.A. / Kirsch, J.F. / Handel, T.M.
External linksJ. Mol. Biol. / PubMed:18775544
MethodsX-ray diffraction
Resolution1.7 - 1.75 Å
Structure data

PDB-3c4o:
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3c4p:
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M complex
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • klebsiella pneumoniae (bacteria)
  • streptomyces clavuligerus (bacteria)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Beta-lactamase / Beta-lactamase inhibitory protein / protein-protein complex / BLIP / SHV-1 / Antibiotic resistance / Hydrolase / Plasmid / Secreted / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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