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TitleHow the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.
Journal, issue, pagesJ. Mol. Biol., Vol. 383, Page 1112-1128, Year 2008
Publish dateNov 8, 2005 (structure data deposition date)
AuthorsBourbigot, S. / Ramalanjaona, N. / Boudier, C. / Salgado, G.F. / Roques, B.P. / Mely, Y. / Bouaziz, S. / Morellet, N.
External linksJ. Mol. Biol. / PubMed:18773912
MethodsNMR (solution)
Structure data

PDB-2exf:
Solution structure of the HIV-1 nucleocapsid (NCp7(12-55)) complexed with the DNA (-) Primer Binding Site
Method: SOLUTION NMR

PDB-2jzw:
How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

KeywordsViral Protein/DNA / protein-DNA complex / stem-loop / bulge / zinc-finger / Viral Protein-DNA COMPLEX / human immunodeficiency virus type 1 (HIV-1) / nuclear magnetic resonance (NMR) / nucleocapsid protein (NCp7) / primer binding site (PBS) / exchange

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