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TitleDiscovery of a novel class of PPARdelta partial agonists
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 18, Page 5018-5022, Year 2008
Publish dateJul 25, 2008 (structure data deposition date)
AuthorsShearer, B.G. / Patel, H.S. / Billin, A.N. / Way, J.M. / Winegar, D.A. / Lambert, M.H. / Xu, R.X. / Leesnitzer, L.M. / Merrihew, R.V. / Huet, S. / Willson, T.M.
External linksBioorg. Med. Chem. Lett. / PubMed:18722772
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-3dy6:
PPARdelta complexed with an anthranilic acid partial agonist
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-DY6:
2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR / nulear receptor / Activator / DNA-binding / Metal-binding / Nucleus / Transcription regulation / Zinc-finger

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