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TitleInteraction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein.
Journal, issue, pagesBiochemistry, Vol. 47, Page 9811-, Year 2008
Publish dateApr 24, 2008 (structure data deposition date)
AuthorsNikolovska-Coleska, Z. / Meagher, J.L. / Jiang, S. / Yang, C.Y. / Qiu, S. / Roller, P.P. / Stuckey, J.A. / Wang, S.
External linksBiochemistry / PubMed:18717598
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2vsl:
Crystal Structure of XIAP BIR3 with a Bivalent Smac Mimetic
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsLIGASE / ZINC-FINGER / POLYMORPHISM / SMAC MIMETIC / METAL-BINDING / UBL CONJUGATION PATHWAY / THIOL PROTEASE INHIBITOR / PHOSPHOPROTEIN / UBL CONJUGATION / PROTEASE INHIBITOR / BIR3 / ZINC / XIAP / APOPTOSIS / CYTOPLASM / HYDROLASE INHIBITOR

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