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TitleKap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
Journal, issue, pagesJ. Mol. Biol., Vol. 383, Page 772-782, Year 2008
Publish dateAug 24, 2008 (structure data deposition date)
AuthorsForwood, J.K. / Lonhienne, T.G. / Marfori, M. / Robin, G. / Meng, W. / Guncar, G. / Liu, S.M. / Stewart, M. / Carroll, B.J. / Kobe, B.
External linksJ. Mol. Biol. / PubMed:18708071
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3ea5:
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSPORT PROTEIN / Karyopherin / Importin / Ran / GTP-binding / Host-virus interaction / Nucleotide-binding / Nucleus / Phosphoprotein / Protein transport / Transport

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