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-Structure paper
Title | Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 64, Page 977-984, Year 2008 |
Publish date | May 22, 2008 (structure data deposition date) |
![]() | Cody, V. / Pace, J. / Rosowsky, A. |
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Methods | X-ray diffraction |
Resolution | 1.4 - 1.9 Å |
Structure data | ![]() PDB-3d80: ![]() PDB-3d84: |
Chemicals | ![]() ChemComp-NDP: ![]() ChemComp-Q22: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / mouse holo enzyme ternary ligand complex dihydrofolate reductase / NADP / One-carbon metabolism / mouse DHFR holo enzyme and ternary ligand complex |