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-Structure paper
Title | 4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 4482-4485, Year 2008 |
Publish date | Jun 4, 2008 (structure data deposition date) |
![]() | Shafer, C.M. / Lindvall, M. / Bellamacina, C. / Gesner, T.G. / Yabannavar, A. / Jia, W. / Lin, S. / Walter, A. |
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Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | ![]() PDB-3dcv: |
Chemicals | ![]() ChemComp-55E: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Ser/Thr protein kinase / nucleotide-binding / phsphorylation / ATP-binding / cancer / oncogene / Alternative initiation / Cytoplasm / Manganese / Membrane / Metal-binding / Nucleus / Phosphoprotein / Polymorphism / Proto-oncogene / Serine/threonine-protein kinase |