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Structure paper

TitleStructure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
Journal, issue, pagesJ. Mol. Biol., Vol. 382, Page 434-447, Year 2008
Publish dateJun 7, 2008 (structure data deposition date)
AuthorsSaad, J.S. / Ablan, S.D. / Ghanam, R.H. / Kim, A. / Andrews, K. / Nagashima, K. / Soheilian, F. / Freed, E.O. / Summers, M.F.
External linksJ. Mol. Biol. / PubMed:18657545
MethodsNMR (solution)
Structure data

PDB-2k4e:
Solution structure of the HIV-2 UNMYRISTOYLATED MATRIX PROTEIN
Method: SOLUTION NMR

PDB-2k4h:
Solution structure of the HIV-2 myristoylated Matrix protein
Method: SOLUTION NMR

PDB-2k4i:
Solution structure of HIV-2 myrMA bound to di-C4-PI(4,5)P2
Method: SOLUTION NMR

Chemicals

ChemComp-MYR:
MYRISTIC ACID

ChemComp-PBU:
(2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1

Source
  • human immunodeficiency virus type 2
KeywordsSTRUCTURAL PROTEIN / AIDS / CAPSID PROTEIN / MYRISTATE / MATRIX / GAG / HIV / VIRION / PLASMA MEMBRANE

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