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TitleStructural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
Journal, issue, pagesBmc Struct. Biol., Vol. 8, Page 32-32, Year 2008
Publish dateDec 4, 2007 (structure data deposition date)
AuthorsGabison, L. / Prange, T. / Colloc'h, N. / El Hajji, M. / Castro, B. / Chiadmi, M.
External linksBmc Struct. Biol. / PubMed:18638417
MethodsX-ray diffraction
Resolution1.6 - 1.8 Å
Structure data

PDB-3bjp:
Urate oxidase cyanide uric acid ternary complex
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3bk8:
Urate oxidase aza-xanthine complex in cyanide
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CYN:
CYANIDE ION

ChemComp-ACE:
ACETYL GROUP

ChemComp-URC:
URIC ACID

ChemComp-HOH:
WATER

ChemComp-AZA:
8-AZAXANTHINE

Source
  • aspergillus flavus (mold)
KeywordsOXIDOREDUCTASE / uric acid / cyanide / inhibition / degradation mechanism / Acetylation / Peroxisome / Purine metabolism

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