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Structure paper

TitleAtomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Journal, issue, pagesProtein Sci., Vol. 17, Page 1467-1474, Year 2008
Publish dateJun 12, 2008 (structure data deposition date)
AuthorsWiltzius, J.J. / Sievers, S.A. / Sawaya, M.R. / Cascio, D. / Popov, D. / Riekel, C. / Eisenberg, D.
External linksProtein Sci. / PubMed:18556473
MethodsX-ray diffraction
Resolution1.66 - 1.8 Å
Structure data

PDB-3dg1:
Segment SSTNVG derived from IAPP
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

PDB-3dgj:
NNFGAIL segment from Islet Amyloid Polypeptide (IAPP or amylin)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

KeywordsPROTEIN FIBRIL / steric zipper / IAPP / SSTNVG / Amyloid / amylin

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