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Structure paper

TitleStructural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 15, Page 811-, Year 2008
Publish dateMay 27, 2008 (structure data deposition date)
AuthorsBrueckner, F. / Cramer, P.
External linksNat. Struct. Mol. Biol. / PubMed:18552824
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-2vum:
Alpha-amanitin inhibited complete RNA polymerase II elongation complex
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • amanita phalloides (death cap)
  • synthetic construct (others)
KeywordsTRANSFERASE / DNA-DIRECTED RNA POLYMERASE / ALPHA-AMANITIN / UBL CONJUGATION / NUCLEAR PROTEIN / RNA POLYMERASE II / ELONGATION COMPLEX / MRNA PROCESSING / PHOSPHORYLATION / ENZYME INHIBITION / DNA DAMAGE / DNA REPAIR / ZINC-FINGER / DNA-BINDING / TRANSFERASE/DNA/RNA / TRANSCRIPTION BUBBLE / ZINC / NUCLEUS / CYTOPLASM / INHIBITOR / MAGNESIUM / TRANSCRIPTION INHIBITION / TRANSLOCATION INTERMEDIATE / TRANSCRIPTION / METAL-BINDING / PHOSPHOPROTEIN / INTERMEDIATE / FUNGAL TOXIN / POLYMORPHISM / NUCLEOTIDYLTRANSFERASE / TRANSCRIPTION MECHANISM

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