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TitleCrystal Structure of a Chimera of Human and Plasmodium Falciparum Hypoxanthine Guanine Phosphoribosyltransferases Provides Insights Into Oligomerization.
Journal, issue, pagesProteins, Vol. 73, Page 1010-, Year 2008
Publish dateNov 2, 2007 (structure data deposition date)
AuthorsGayathri, P. / Sujay Subbayya, I.N. / Ashok, C.S. / Selvi, T.S. / Balaram, H. / Murthy, M.R.N.
External linksProteins / PubMed:18536021
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2vfa:
Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • homo sapiens (human)
KeywordsTRANSFERASE / HYPOXANTHINE-GUANINE PHOSPHORIBOSYL TRANSFERASE (HGPRT) / PURINE SALVAGE / DISEASE MUTATION / GLYCOSYLTRANSFERASE / METAL-BINDING / GOUT / CHIMERA / MAGNESIUM

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