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-Structure paper
Title | Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. |
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Journal, issue, pages | J. Biol. Chem., Vol. 283, Page 22815-22825, Year 2008 |
Publish date | Feb 22, 2008 (structure data deposition date) |
![]() | Redzynia, I. / Ljunggren, A. / Abrahamson, M. / Mort, J.S. / Krupa, J.C. / Jaskolski, M. / Bujacz, G. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.67 Å |
Structure data | ![]() PDB-3cbj: ![]() PDB-3cbk: |
Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / chagasin / cathepsin B / occluding loop / Chagas disease / Glycoprotein / Hydrolase / Lysosome / Protease / Thiol protease / Zymogen / Cytoplasmic vesicle / Protease inhibitor / Thiol protease inhibitor / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |