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TitleThe structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 21198-21210, Year 2008
Publish dateJan 14, 2008 (structure data deposition date)
AuthorsWan, Z.L. / Huang, K. / Hu, S.Q. / Whittaker, J. / Weiss, M.A.
External linksJ. Biol. Chem. / PubMed:18492668
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-3bxq:
The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

KeywordsHORMONE / TR transition / Electrostatic block / Protein allostery / Receptor binding

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