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Structure paper

TitleCatalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex.
Journal, issue, pagesBiochemistry, Vol. 47, Page 5736-5745, Year 2008
Publish dateDec 17, 2007 (structure data deposition date)
AuthorsSilvaggi, N.R. / Wilson, D. / Tzipori, S. / Allen, K.N.
External linksBiochemistry / PubMed:18457419
MethodsX-ray diffraction
Resolution1.2 - 1.4 Å
Structure data

PDB-3bok:
Structure of the C. botulinum neurotoxin serotype A apo-enzyme
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-3bon:
Structure of the C. botulinum neurotoxin serotype A with Zn2+ cofactor bound
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-3boo:
Structure of the C. botulinum neurotoxin serotype A with an inhibitory peptide bound
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

Source
  • clostridium botulinum (bacteria)
KeywordsTOXIN / botulinum / neurotoxin / metalloprotease / TOXIN/TOXIN INHIBITOR / peptidic inhibitor / TOXIN-TOXIN INHIBITOR COMPLEX

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