EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
ジャーナル・号・ページ	J. Mol. Biol., Vol. 379, Page 505-519, Year 2008
掲載日	2008年2月23日 (構造データの登録日)
著者	Blaha, G. / Gurel, G. / Schroeder, S.J. / Moore, P.B. / Steitz, T.A.
リンク	J. Mol. Biol. / PubMed:18455733
手法	X線回折
解像度	2.4 - 3.3 Å
構造データ	PDB-3cc2: The Refined Crystal Structure of the Haloarcula Marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution with rrnA Sequence for the 23S rRNA and Genome-derived Sequences for r-Proteins 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-3cc4: Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-3cc7: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation C2487U 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-3cce: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535A 手法: X-RAY DIFFRACTION / 解像度: 2.75 Å PDB-3ccj: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation C2534U 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å PDB-3ccl: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535C. Density for Anisomycin is visible but not included in model. 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-3ccm: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2611U 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-3ccq: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-3ccr: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488C. Density for anisomycin is visible but not included in the model. 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-3ccs: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482A 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-3ccu: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-3ccv: Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-3cd6: Co-cystal of large Ribosomal Subunit mutant G2616A with CC-Puromycin 手法: X-RAY DIFFRACTION / 解像度: 2.75 Å
化合物	ChemComp-MG: Unknown entry ChemComp-NA: Unknown entry ChemComp-CL: Unknown entry ChemComp-CD: Unknown entry ChemComp-K: Unknown entry ChemComp-HOH: WATER ChemComp-SR: STRONTIUM ION ChemComp-ANM: ANISOMYCIN
由来	haloarcula marismortui (好塩性)
キーワード	RIBOSOME / genomic sequnece for r-proteins / Ribonucleoprotein / Ribosomal protein / RNA-binding / rRNA-binding / tRNA-binding / Metal-binding / Zinc-finger / wild type / large ribosomal subunit / Haloarcula marismortui / co-crystal / anisomycin / anisomycin resistance / C2487U / 23S rRNA / 23S rRNA mutation U2535A / C2534U mutation / U2535C mutation / G2611U mutation / A2488C mutation / G2482A mutation / G2482C mutation / G2616A mutation / CC-Puromycin