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Structure paper

TitleRevealing the Moonlighting Role of Nadp in the Structure of a Flavin-Containing Monooxygenase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 105, Page 6572-, Year 2008
Publish dateMar 12, 2008 (structure data deposition date)
AuthorsAlfieri, A. / Malito, E. / Orru, R. / Fraaije, M.W. / Mattevi, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:18443301
MethodsX-ray diffraction
Resolution2.6 - 2.8 Å
Structure data

PDB-2vq7:
Bacterial flavin-containing monooxygenase in complex with NADP: native data
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2vqb:
Bacterial flavin-containing monooxygenase in complex with NADP: soaking in aerated solution
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-CL:
Unknown entry

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-OXY:
OXYGEN MOLECULE

Source
  • methylophaga sp. sk1 (bacteria)
KeywordsOXIDOREDUCTASE / NADP / OXYGEN / FLAVIN / DRUG METABOLISM NADP / MONOOXYGENASE / DRUG METABOLISM

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