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-Structure paper
Title | Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. Usa, Vol. 105, Page 5349-5354, Year 2008 |
Publish date | Sep 26, 2007 (structure data deposition date) |
Authors | Ames, B.D. / Korman, T.P. / Zhang, W. / Smith, P. / Vu, T. / Tang, Y. / Tsai, S.C. |
External links | Proc. Natl. Acad. Sci. Usa / PubMed:18388203 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.2 Å |
Structure data | PDB-2rer: PDB-2res: PDB-2rez: |
Chemicals | ChemComp-HOH: ChemComp-ACT: ChemComp-IOD: |
Source |
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Keywords | BIOSYNTHETIC PROTEIN / CYCLASE / AROMATASE / POLYKETIDE / HELIX-GRIP / DEHYDRATASE / ANTICANCER / ANTIBIOTIC / Antibiotic biosynthesis / Methyltransferase / Multifunctional enzyme / Transferase / TETRACENOMYCIN / LYASE / DOUBLE-HOT-DOG |