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Structure paper

TitleThe lattice as allosteric effector: structural studies of alphabeta- and gamma-tubulin clarify the role of GTP in microtubule assembly
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 5378-5383, Year 2008
Publish dateFeb 21, 2008 (structure data deposition date)
AuthorsRice, L.M. / Montabana, E.A. / Agard, D.A.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18388201
MethodsX-ray diffraction
Resolution2.303 Å
Structure data

PDB-3cb2:
Crystal structure of human gamma-tubulin bound to GDP
Method: X-RAY DIFFRACTION / Resolution: 2.303 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / HYDROLASE / tubulin / lattice / microtubule / nucleation / GTPase / lateral interaction

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