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Structure paper

TitleStructural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 15789-15798, Year 2008
Publish dateApr 7, 2008 (structure data deposition date)
AuthorsGreen, T. / Grigorian, A. / Klyuyeva, A. / Tuganova, A. / Luo, M. / Popov, K.M.
External linksJ. Biol. Chem. / PubMed:18387944
MethodsX-ray diffraction
Resolution2.3 - 2.61 Å
Structure data

PDB-3crk:
Crystal structure of the PDHK2-L2 complex.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3crl:
Crystal structure of the PDHK2-L2 complex.
Method: X-RAY DIFFRACTION / Resolution: 2.61 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsTRANSFERASE / pyruvate dehydrogenase kinase isozyme 2 / glucose metabolism / kinase / mitochondrion / Carbohydrate metabolism / Transit peptide / Acyltransferase / Glycolysis / Lipoyl

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