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-Structure paper
Title | Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production |
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Journal, issue, pages | Mol. Cell. Biol., Vol. 28, Page 3663-3671, Year 2008 |
Publish date | Feb 8, 2008 (structure data deposition date) |
![]() | Shimizu, H. / Tosaki, A. / Kaneko, K. / Hisano, T. / Sakurai, T. / Nukina, N. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.7 Å |
Structure data | ![]() PDB-2zhr: ![]() PDB-2zhs: ![]() PDB-2zht: ![]() PDB-2zhu: ![]() PDB-2zhv: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE inhibitor / OM99-2 complex / pH 5.0 / Aspartyl protease / Glycoprotein / Membrane / Protease / Transmembrane / Zymogen / HYDROLASE-HYDROLASE inhibitor COMPLEX / HYDROLASE / pH 4.0 / Alternative splicing / pH 4.5 / pH 7.0 |