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Structure paper

TitleStructures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 16169-, Year 2008
Publish dateMar 28, 2008 (structure data deposition date)
AuthorsCao, X. / Antonyuk, S. / Seetharaman, S.V. / Whitson, L.J. / Taylor, A.B. / Holloway, S.P. / Strange, R.W. / Doucette, P.A. / Valentine, J.S. / Tiwari, A. ...Cao, X. / Antonyuk, S. / Seetharaman, S.V. / Whitson, L.J. / Taylor, A.B. / Holloway, S.P. / Strange, R.W. / Doucette, P.A. / Valentine, J.S. / Tiwari, A. / Hayward, L.J. / Padua, S. / Cohlberg, J.A. / Hasnain, S.S. / Hart, P.J.
External linksJ. Biol. Chem. / PubMed:18378676
MethodsX-ray diffraction
Resolution1.3 - 1.95 Å
Structure data

PDB-2vr6:
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-2vr7:
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-2vr8:
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

PDB-3cqp:
Human SOD1 G85R Variant, Structure I
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-3cqq:
Human SOD1 G85R Variant, Structure II
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CU:
COPPER (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-SCN:
THIOCYANATE ION

ChemComp-HOH:
WATER

ChemComp-MLI:
MALONATE ION

ChemComp-ACE:
ACETYL GROUP

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / ZINC / COPPER / HUMAN CU / CYTOPLASM / ACETYLATION / UBL CONJUGATION / DISEASE MUTATION / ZN SUPEROXIDE DISMUTASE / AMYOTROPHIC LATERAL SCLEROSIS / ANTIOXIDANT / METAL-BINDING

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