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Structure paper

TitleSubstrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.
Journal, issue, pagesEmbo Rep., Vol. 9, Page 459-464, Year 2008
Publish dateJan 31, 2008 (structure data deposition date)
AuthorsBebenek, K. / Garcia-Diaz, M. / Foley, M.C. / Pedersen, L.C. / Schlick, T. / Kunkel, T.A.
External linksEmbo Rep. / PubMed:18369368
MethodsX-ray diffraction
Resolution2.2 - 2.25 Å
Structure data

PDB-3c5f:
Structure of a binary complex of the R517A Pol lambda mutant
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-3c5g:
Structure of a ternary complex of the R517K Pol lambda mutant
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-D3T:
2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsTransferase / Lyase/DNA / helix hairpin helix / DNA damage / DNA repair / DNA replication / DNA synthesis / DNA-binding / DNA-directed DNA polymerase / Lyase / Manganese / Metal-binding / Nucleotidyltransferase / Nucleus / Phosphoprotein / Polymorphism / Lyase-DNA COMPLEX / Transferase/DNA / helix-hairpin-helix / Transferase-DNA

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