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TitleKemp elimination catalysts by computational enzyme design.
Journal, issue, pagesNature, Vol. 453, Page 190-195, Year 2008
Publish dateOct 18, 2007 (structure data deposition date)
AuthorsRothlisberger, D. / Khersonsky, O. / Wollacott, A.M. / Jiang, L. / DeChancie, J. / Betker, J. / Gallaher, J.L. / Althoff, E.A. / Zanghellini, A. / Dym, O. ...Rothlisberger, D. / Khersonsky, O. / Wollacott, A.M. / Jiang, L. / DeChancie, J. / Betker, J. / Gallaher, J.L. / Althoff, E.A. / Zanghellini, A. / Dym, O. / Albeck, S. / Houk, K.N. / Tawfik, D.S. / Baker, D.
External linksNature / PubMed:18354394
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-2rkx:
The 3D structure of chain D, cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-HOH:
WATER

KeywordsLYASE / Alpha-Beta Barrel / Structural Genomics / Israel Structural Proteomics Center / ISPC / Amino-acid biosynthesis / Cytoplasm / Histidine biosynthesis

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