EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ジャーナル・号・ページ	Nat. Chem. Biol., Vol. 4, Page 241-247, Year 2008
掲載日	2005年9月16日 (構造データの登録日)
著者	Nettles, K.W. / Bruning, J.B. / Gil, G. / Nowak, J. / Sharma, S.K. / Hahm, J.B. / Kulp, K. / Hochberg, R.B. / Zhou, H. / Katzenellenbogen, J.A. ...Nettles, K.W. / Bruning, J.B. / Gil, G. / Nowak, J. / Sharma, S.K. / Hahm, J.B. / Kulp, K. / Hochberg, R.B. / Zhou, H. / Katzenellenbogen, J.A. / Katzenellenbogen, B.S. / Kim, Y. / Joachmiak, A. / Greene, G.L.
リンク	Nat. Chem. Biol. / PubMed:18344977
手法	X線回折
解像度	1.85 - 2.7 Å
構造データ	PDB-2b23: Human estrogen receptor alpha ligand-binding domain and a glucocorticoid receptor-interacting protein 1 NR box II peptide 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-2qa6: Crystal Structure of Estrogen Receptor Alpha mutant 537S Complexed with 4-(6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-2qa8: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with Genistein 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-2qab: Crystal Structure of Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with an Ethyl Indazole Compound 手法: X-RAY DIFFRACTION / 解像度: 1.89 Å PDB-2qgt: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-2qgw: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with a Chloro-Indazole Compound 手法: X-RAY DIFFRACTION / 解像度: 2.39 Å PDB-2qh6: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with an Oxabicyclic diarylethylene Compound 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-2qr9: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with an Oxabicyclic Derivative Compound 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-2qse: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain complexed with Burned Meat Compound 4-OH-PhIP 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-2qxm: Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Burned Meat Compound PhIP 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å
化合物	ChemComp-HOH: WATER / 水 ChemComp-KN2: 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL / 3-(2,4-ジヒドロキシフェニル)-1H-インダゾ-ル-6-オ-ル ChemComp-GEN: GENISTEIN / ゲニステイン[フラボノイド] / 阻害剤YM / ゲニステイン ChemComp-EI1: 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ChemComp-EED: (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ChemComp-EES: 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL / 2-(p-ヒドロキシフェニル)-3-クロロ-2H-インダゾ-ル-5-オ-ル ChemComp-ODE: DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ChemComp-HZ3: dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ChemComp-1HP: 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol / 4′-OH-PhIP ChemComp-PIQ*: 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE / PhIP / 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
由来	homo sapiens (ヒト) mus musculus (ハツカネズミ)
キーワード	HORMONE/GROWTH FACTOR RECEPTOR / ESTROGEN RECEPTOR (エストロゲン受容体) / LBD / GRIP PEPTIDE / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX / TRANSCRIPTION (転写 (生物学)) / Protein-Ligand Complex / DNA-binding / Lipid-binding / Metal-binding / Nucleus (Nucleus) / Phosphorylation (リン酸化) / Receptor / Steroid-binding / Transcription regulation / Zinc-finger (ジンクフィンガー)