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TitleSubtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
Journal, issue, pagesJ. Mol. Biol., Vol. 377, Page 1297-1303, Year 2008
Publish dateJan 17, 2008 (structure data deposition date)
AuthorsHoare, H.L. / Sullivan, L.C. / Clements, C.S. / Ely, L.K. / Beddoe, T. / Henderson, K.N. / Lin, J. / Reid, H.H. / Brooks, A.G. / Rossjohn, J.
External linksJ. Mol. Biol. / PubMed:18339401
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3bze:
The human non-classical major histocompatibility complex molecule HLA-E
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3bzf:
The human non-classical major histocompatibility complex molecule HLA-E
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MHC fold / Transmembrane / Disease mutation / Glycation / Glycoprotein / Immune response / Immunoglobulin domain / MHC I / Pyrrolidone carboxylic acid / Secreted / Membrane / Polymorphism / Host-virus interaction / Ubl conjugation

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