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TitleDesign of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 14703-14716, Year 2008
Publish dateJan 11, 2008 (structure data deposition date)
AuthorsHua, Q.X. / Nakagawa, S.H. / Jia, W. / Huang, K. / Phillips, N.B. / Hu, S.Q. / Weiss, M.A.
External linksJ. Biol. Chem. / PubMed:18332129
MethodsNMR (solution)
Structure data

PDB-2jzq:
Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures
Method: SOLUTION NMR

KeywordsHORMONE / SINGLE CHAIN INSULIN / MUTANT / Carbohydrate metabolism / Cleavage on pair of basic residues / Diabetes mellitus / Disease mutation / Glucose metabolism / Pharmaceutical / Secreted

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