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TitleCrystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Journal, issue, pagesBmc Struct. Biol., Vol. 8, Page 13-13, Year 2008
Publish dateSep 26, 2007 (structure data deposition date)
AuthorsParkinson, G.N. / Vines, D. / Driscoll, P.C. / Djordjevic, S.
External linksBmc Struct. Biol. / PubMed:18312637
MethodsX-ray diffraction
Resolution2.1 - 2.5 Å
Structure data

PDB-2rea:
Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding.
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2red:
Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding.
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PX DOMAIN / PI3K / KINASE / PHOSPHORYLATION / NUCLEAR PROTEIN / PHOSPHOINOSITIDE / Cytoplasm / Cytoplasmic vesicle / Golgi apparatus / Membrane / Nucleus / Polymorphism

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