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| Title | T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 283, Page 9168-9176, Year 2008 |
| Publish date | Oct 14, 2009 (structure data deposition date) |
Authors | Li, Y. / Wang, Z. / Furukawa, N. / Escaron, P. / Weiszmann, J. / Lee, G. / Lindstrom, M. / Liu, J. / Liu, X. / Xu, H. ...Li, Y. / Wang, Z. / Furukawa, N. / Escaron, P. / Weiszmann, J. / Lee, G. / Lindstrom, M. / Liu, J. / Liu, X. / Xu, H. / Plotnikova, O. / Prasad, V. / Walker, N. / Learned, R.M. / Chen, J.-L. |
External links | J. Biol. Chem. / PubMed:18263587 |
| Methods | X-ray diffraction |
| Resolution | 2.55 Å |
| Structure data | ![]() PDB-3k8s: |
| Chemicals | ![]() ChemComp-Z27: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSCRIPTION / PPARgamma / ligand binding pocket / ligand / diabetic / Activator / Alternative splicing / Diabetes mellitus / Disease mutation / DNA-binding / Metal-binding / Nucleus / Obesity / Phosphoprotein / Polymorphism / Receptor / Transcription regulation / Zinc / Zinc-finger / LBD and ligand binding domain |
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homo sapiens (human)
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