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Structure paper

TitleC1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition.
Journal, issue, pagesJ. Immunol., Vol. 180, Page 2329-2338, Year 2008
Publish dateFeb 9, 2007 (structure data deposition date)
AuthorsPaidassi, H. / Tacnet-Delorme, P. / Garlatti, V. / Darnault, C. / Ghebrehiwet, B. / Gaboriaud, C. / Arlaud, G.J. / Frachet, P.
External linksJ. Immunol. / PubMed:18250442
MethodsX-ray diffraction
Resolution1.9 - 2.05 Å
Structure data

PDB-2jg8:
Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2jg9:
Crystallographic structure of human C1q globular heads (P1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

ChemComp-SEP:
PHOSPHOSERINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / POLYMORPHISM / GLYCOPROTEIN / PHAGOCYTOSIS / DISEASE MUTATION / COMPLEMENT PATHWAY / CELL SURFACE MOLECULE / PYRROLIDONE CARBOXYLIC ACID / HYDROXYLATION / INNATE IMMUNITY / IMMUNE RESPONSE / COLLAGEN / TOLERANCE / APOPOTOSIS / COMPLEMENT

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