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Structure paper

TitleThe C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Journal, issue, pagesMol. Cell, Vol. 29, Page 169-179, Year 2008
Publish dateJun 27, 2007 (structure data deposition date)
AuthorsCui, S. / Eisenacher, K. / Kirchhofer, A. / Brzozka, K. / Lammens, A. / Lammens, K. / Fujita, T. / Conzelmann, K.K. / Krug, A. / Hopfner, K.P.
External linksMol. Cell / PubMed:18243112
MethodsX-ray diffraction
Resolution2.7 - 3 Å
Structure data

PDB-2qfb:
Crystal structure of the regulatory domain of human RIG-I with bound Zn
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2qfd:
Crystal structure of the regulatory domain of human RIG-I with bound Hg
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-HG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Zinc finger / Alternative splicing / Antiviral defense / ATP-binding / Helicase / Immune response / Innate immunity / Interferon induction / Nucleotide-binding / Polymorphism / RNA-binding / Ubl conjugation

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