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Structure paper

TitleStructure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 5876-5887, Year 2008
Publish dateJul 6, 2007 (structure data deposition date)
AuthorsKotzsch, A. / Nickel, J. / Seher, A. / Heinecke, K. / van Geersdaele, L. / Herrmann, T. / Sebald, W. / Mueller, T.D.
External linksJ. Biol. Chem. / PubMed:18160401
MethodsX-ray diffraction
Resolution2.44 - 2.6 Å
Structure data

PDB-2qj9:
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
Method: X-RAY DIFFRACTION / Resolution: 2.44 Å

PDB-2qja:
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2qjb:
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCytokine/Receptor / ligand-receptor complex / Chondrogenesis / Cleavage on pair of basic residues / Cytokine / Developmental protein / Differentiation / Glycoprotein / Growth factor / Osteogenesis / ATP-binding / Disease mutation / Kinase / Magnesium / Manganese / Membrane / Metal-binding / Nucleotide-binding / Phosphorylation / Serine/threonine-protein kinase / Transferase / Transmembrane / Cytokine-Receptor COMPLEX

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