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Structure paper

TitleStructures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds.
Journal, issue, pagesImmunity, Vol. 27, Page 941-951, Year 2007
Publish dateNov 30, 2007 (structure data deposition date)
AuthorsSantiago, C. / Ballesteros, A. / Martinez-Munoz, L. / Mellado, M. / Kaplan, G.G. / Freeman, G.J. / Casasnovas, J.M.
External linksImmunity / PubMed:18083575
MethodsX-ray diffraction
Resolution2.2 - 2.95 Å
Structure data

PDB-3bi9:
Tim-4
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-3bia:
Tim-4 in complex with sodium potassium tartrate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3bib:
Tim-4 in complex with phosphatidylserine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-PSF:
1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / BETA BARREL / IMMUNOGLOBULIN FOLD / IgV DOMAIN / TIM / Glycoprotein / Immunoglobulin domain / Membrane / Polymorphism / Transmembrane

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