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Structure paper

TitleStructure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
Journal, issue, pagesJ. Mol. Biol., Vol. 375, Page 969-978, Year 2008
Publish dateJul 30, 2007 (structure data deposition date)
AuthorsBell, C.H. / Pantophlet, R. / Schiefner, A. / Cavacini, L.A. / Stanfield, R.L. / Burton, D.R. / Wilson, I.A.
External linksJ. Mol. Biol. / PubMed:18068724
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2qsc:
Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab-peptide complex / HIV-1 / gp120 / V3 loop / immunoglobulin fold / AIDS / Apoptosis / Envelope protein / Fusion protein / Glycoprotein / Host-virus interaction / Membrane / Transmembrane / Viral immunoevasion / Virion

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