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-Structure paper
Title | Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. Usa, Vol. 104, Page 19802-19807, Year 2007 |
Publish date | Oct 19, 2007 (structure data deposition date) |
![]() | Lew, E.D. / Bae, J.H. / Rohmann, E. / Wollnik, B. / Schlessinger, J. |
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Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | ![]() PDB-3b2t: |
Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-M33: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / phosphotransferase / cell signaling / Alternative splicing / ATP-binding / Disease mutation / Ectodermal dysplasia / Glycoprotein / Heparin-binding / Immunoglobulin domain / Kinase / Lacrimo-auriculo-dento-digital syndrome / Membrane / Nucleotide-binding / Phosphorylation / Polymorphism / Receptor / Secreted / Transmembrane / Tyrosine-protein kinase |