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Structure paper

Title(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 129, Page 15412-15413, Year 2007
Publish dateMay 14, 2007 (structure data deposition date)
AuthorsMcKenna, C.E. / Kashemirov, B.A. / Upton, T.G. / Batra, V.K. / Goodman, M.F. / Pedersen, L.C. / Beard, W.A. / Wilson, S.H.
External linksJ. Am. Chem. Soc. / PubMed:18031037
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2pxi:
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GFH:
2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / TRANSFERASE/DNA / Nucleotidyl Transferase / DNA polymerase / chiral Interaction / stereoselectivity / TRANSFERASE-DNA COMPLEX

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