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TitleHigh resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 1501-1507, Year 2008
Publish dateNov 2, 2007 (structure data deposition date)
AuthorsShieh, H.S. / Mathis, K.J. / Williams, J.M. / Hills, R.L. / Wiese, J.F. / Benson, T.E. / Kiefer, J.R. / Marino, M.H. / Carroll, J.N. / Leone, J.W. ...Shieh, H.S. / Mathis, K.J. / Williams, J.M. / Hills, R.L. / Wiese, J.F. / Benson, T.E. / Kiefer, J.R. / Marino, M.H. / Carroll, J.N. / Leone, J.W. / Malfait, A.M. / Arner, E.C. / Tortorella, M.D. / Tomasselli, A.
External linksJ. Biol. Chem. / PubMed:17991750
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-3b8z:
High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-294:
N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / alpha/beta

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