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TitleStructural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
Journal, issue, pagesProtein Sci., Vol. 16, Page 2454-2471, Year 2007
Publish dateMar 1, 2007 (structure data deposition date)
AuthorsRunyon, S.T. / Zhang, Y. / Appleton, B.A. / Sazinsky, S.L. / Wu, P. / Pan, B. / Wiesmann, C. / Skelton, N.J. / Sidhu, S.S.
External linksProtein Sci. / PubMed:17962403
MethodsNMR (solution) / X-ray diffraction
Resolution1.7 Å
Structure data

PDB-2joa:
HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances
Method: SOLUTION NMR

PDB-2p3w:
Crystal Structure of the HtrA3 PDZ Domain Bound to a Phage-Derived Ligand (FGRWV)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / PDZ / beta-sandwich / cyclically-permuted / PDZ DOMAIN / PHAGE DERIVED HIGH AFFINITY LIGAND

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