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-Structure paper
Title | The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 6056-6061, Year 2007 |
Publish date | Sep 18, 2007 (structure data deposition date) |
![]() | Yuan, C. / St Jean, D.J. / Liu, Q. / Cai, L. / Li, A. / Han, N. / Moniz, G. / Askew, B. / Hungate, R.W. / Johansson, L. ...Yuan, C. / St Jean, D.J. / Liu, Q. / Cai, L. / Li, A. / Han, N. / Moniz, G. / Askew, B. / Hungate, R.W. / Johansson, L. / Tedenborg, L. / Pyring, D. / Williams, M. / Hale, C. / Chen, M. / Cupples, R. / Zhang, J. / Jordan, S. / Bartberger, M.D. / Sun, Y. / Emery, M. / Wang, M. / Fotsch, C. |
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Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-2rbe: |
Chemicals | ![]() ChemComp-ZMG: ![]() ChemComp-NDP: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / Alpha Beta / 3-Layer(aba) Sandwich / Rossmann fold / NAD(P)-binding Rossmann-like Domain / Endoplasmic reticulum / Glycoprotein / Lipid metabolism / Membrane / Microsome / NADP / Signal-anchor / Steroid metabolism / Transmembrane / Polymorphism |