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TitleSolution Structure of the A4 Domain of Factor Xi Sheds Light on the Mechanism of Zymogen Activation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 104, Page 15693-, Year 2007
Publish dateOct 25, 2006 (structure data deposition date)
AuthorsSamuel, D. / Cheng, H. / Riley, P.W. / Canutescu, A.A. / Nagaswami, C. / Weisel, J.W. / Bu, Z. / Walsh, P.N. / Roder, H.
External linksProc. Natl. Acad. Sci. USA / PubMed:17884987
MethodsNMR (solution)
Structure data

PDB-2j8j:
Solution Structure of the A4 Domain of Blood Coagulation Factor XI
Method: SOLUTION NMR

PDB-2j8l:
FXI Apple 4 domain loop-out conformation
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PROTEASE / GLYCOPROTEIN / POLYMORPHISM / SERINE PROTEASE / HEPARIN-BINDING / DISEASE MUTATION / FXI / BLOOD COAGULATION / PAN DOMAIN /APPLE DOMAIN / BLOOD COAGULATION / ALTERNATIVE SPLICING

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