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TitleDesign and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 17, Page 5686-5689, Year 2007
Publish dateDec 6, 2006 (structure data deposition date)
AuthorsShin, D. / Lee, S.C. / Heo, Y.S. / Lee, W.Y. / Cho, Y.S. / Kim, Y.E. / Hyun, Y.L. / Cho, J.M. / Lee, Y.S. / Ro, S.
External linksBioorg. Med. Chem. Lett. / PubMed:17764934
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-2o5k:
Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-HBM:
2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / GSK3beta / benzoimidazol inhibitor

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