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TitleConformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 104, Page 14336-14341, Year 2007
Publish dateJul 18, 2007 (structure data deposition date)
AuthorsMurphy, J.M. / Korzhnev, D.M. / Ceccarelli, D.F. / Briant, D.J. / Zarrine-Afsar, A. / Sicheri, F. / Kay, L.E. / Pawson, T.
External linksProc. Natl. Acad. Sci. Usa / PubMed:17726107
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2qnj:
Kinase and Ubiquitin-associated domains of MARK3/Par-1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / serine/threonine protein kinase / ubiquitin-associated domain / MARK / PAR-1

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