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Structure paper

TitleStructural engineering of pMHC reagents for T cell vaccines and diagnostics.
Journal, issue, pagesChem. Biol., Vol. 14, Page 909-922, Year 2007
Publish dateJul 28, 2007 (structure data deposition date)
AuthorsMitaksov, V. / Truscott, S.M. / Lybarger, L. / Connolly, J.M. / Hansen, T.H. / Fremont, D.H.
External linksChem. Biol. / PubMed:17719490
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-2qri:
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2qrs:
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2qrt:
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / MHC-I / Ova / Single Chain MHC-I / Glycoprotein / Immune response / Membrane / MHC I / Transmembrane / Single Chain / Ovalbumin

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