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-Structure paper
Title | Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison |
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Journal, issue, pages | J. Mol. Biol., Vol. 372, Page 1070-1081, Year 2007 |
Publish date | Jul 28, 2003 (structure data deposition date) |
Authors | He, X. / van Waardenburg, R.C. / Babaoglu, K. / Price, A.C. / Nitiss, K.C. / Nitiss, J.L. / Bjornsti, M.A. / White, S.W. |
External links | J. Mol. Biol. / PubMed:17707402 |
Methods | X-ray diffraction |
Resolution | 2.03 Å |
Structure data | PDB-1q32: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | REPLICATION / TRANSCRIPTION / HYDROLASE / Tyrosyl-DNA Phosphodiesterase; TDP; DNA repair |