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TitleStructural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
Journal, issue, pagesOncogene, Vol. 27, Page 585-595, Year 2008
Publish dateOct 30, 2006 (structure data deposition date)
AuthorsVeverka, V. / Crabbe, T. / Bird, I. / Lennie, G. / Muskett, F.W. / Taylor, R.J. / Carr, M.D.
External linksOncogene / PubMed:17684489
MethodsNMR (solution)
Structure data

PDB-2npu:
The solution structure of the rapamycin-binding domain of mTOR (FRB)
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Four-helix bundle

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