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Structure paper

TitleStructural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.
Journal, issue, pagesMol. Cell, Vol. 27, Page 474-485, Year 2007
Publish dateJan 25, 2007 (structure data deposition date)
AuthorsPeschard, P. / Kozlov, G. / Lin, T. / Mirza, I.A. / Berghuis, A.M. / Lipkowitz, S. / Park, M. / Gehring, K.
External linksMol. Cell / PubMed:17679095
MethodsX-ray diffraction
Resolution1.56 - 1.9 Å
Structure data

PDB-2ooa:
crystal structure of the UBA domain from Cbl-b ubiquitin ligase
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

PDB-2oob:
crystal structure of the UBA domain from Cbl-b ubiquitin ligase in complex with ubiquitin
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsLIGASE / alpha-helical domain / protein-protein complex

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