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TitleCrystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 27984-27993, Year 2007
Publish dateAug 31, 2006 (structure data deposition date)
AuthorsHong, B.S. / Senisterra, G. / Rabeh, W.M. / Vedadi, M. / Leonardi, R. / Zhang, Y.M. / Rock, C.O. / Jackowski, S. / Park, H.W.
External linksJ. Biol. Chem. / PubMed:17631502
MethodsX-ray diffraction
Resolution1.9 - 2.05 Å
Structure data

PDB-2i7n:
Crystal structure of human PANK1 alpha: the catalytic core domain in complex with AcCoA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2i7p:
Crystal structure of human PANK3 in complex with AcCoA
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-ACO:
ACETYL COENZYME *A

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PANK / Structural Genomics / Structural Genomics Consortium / SGC

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